DSSSB Previous Year MCQs: Ocular Pharmacology
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Q-1: Prophylactic YAG peripheral iridotomy is being done at your clinic. Which drug will you instill in the patient’s eye before the procedure? (2019) (DSSSB Optometrist Previous MCQs)
a. Tropicamide
b. Homatropine
c. Pilocarpine
d. Phenylephrine
Answer: c. Pilocarpine
Prior to performing an Nd:YAG laser peripheral iridotomy, pilocarpine is instilled to induce miosis, causing the pupil to tightly constrict. This action stretches the iris crypts and mechanically thins the peripheral iris, making it easier to penetrate with the laser while minimizing the risk of iris bunching.
Prior to performing an Nd:YAG laser peripheral iridotomy, pilocarpine is instilled to induce miosis, causing the pupil to tightly constrict. This action stretches the iris crypts and mechanically thins the peripheral iris, making it easier to penetrate with the laser while minimizing the risk of iris bunching.
Q-2: Which of the following is a systemic anti-muscarinic agent? (2024) (DSSSB Optometrist Previous MCQs)
a. Carboxymethylcellulose
b. Glycerine
c. Flurbiprofen
d. Atropine
Answer: d. Atropine
Atropine is a highly potent anti-muscarinic agent that competitively blocks acetylcholine at postganglionic parasympathetic receptor sites. While frequently used as a topical cycloplegic in ophthalmology, it can also act systemically to treat conditions like bradycardia or organophosphate poisoning.
Atropine is a highly potent anti-muscarinic agent that competitively blocks acetylcholine at postganglionic parasympathetic receptor sites. While frequently used as a topical cycloplegic in ophthalmology, it can also act systemically to treat conditions like bradycardia or organophosphate poisoning.
Q-3: Nanotechnology-based approaches in ocular drug delivery aim to achieve all of the following, EXCEPT: (2024) (DSSSB Optometrist Previous MCQs)
a. Better ocular absorption
b. Uncontrolled release of the drug
c. Enhanced drug action
d. Advanced penetration through ocular barriers
Answer: b. Uncontrolled release of the drug
Nanotechnology is specifically engineered to improve ocular absorption and allow for sustained, highly controlled, and targeted drug delivery. Uncontrolled or rapid release of a medication is the exact opposite of what these advanced delivery systems are designed to do.
Nanotechnology is specifically engineered to improve ocular absorption and allow for sustained, highly controlled, and targeted drug delivery. Uncontrolled or rapid release of a medication is the exact opposite of what these advanced delivery systems are designed to do.
Q-4: To increase the absorption of topical drug, which of the following methods is NOT used? (2019) (DSSSB Optometrist Previous MCQs)
a. Add surfactants
b. Close eyelids after instillation of drugs
c. Decrease the frequency of instillation
d. Punctal compression
Answer: c. Decrease the frequency of instillation
Decreasing the frequency of eye drop instillation limits the total amount of medication delivered to the ocular surface, thereby reducing overall absorption. Methods like punctal compression, eyelid closure, and formulating drops with surfactants are specifically designed to prolong tissue contact time and enhance drug bioavailability.
Decreasing the frequency of eye drop instillation limits the total amount of medication delivered to the ocular surface, thereby reducing overall absorption. Methods like punctal compression, eyelid closure, and formulating drops with surfactants are specifically designed to prolong tissue contact time and enhance drug bioavailability.
Q-5: The drug delivery system includes: (2019) (DSSSB Optometrist Previous MCQs)
a. Bandage contact lens
b. Spectacles
c. IOL
d. Prisms
Answer: a. Bandage contact lens
Bandage contact lenses can function as an effective ocular drug delivery system by absorbing topical ophthalmic medications and slowly releasing them onto the cornea. Devices like spectacles, intraocular lenses, and prisms serve purely optical or structural purposes and do not deliver pharmacological agents.
Bandage contact lenses can function as an effective ocular drug delivery system by absorbing topical ophthalmic medications and slowly releasing them onto the cornea. Devices like spectacles, intraocular lenses, and prisms serve purely optical or structural purposes and do not deliver pharmacological agents.
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